Dr. Henry Frost Office at 98 Broad Street

Charleston, South Carolina, is known for its cobblestone streets, antebellum architecture, and undeniable Southern charm. But what truly makes the Holy City shine is its collection of distinctive neighborhoods, each with a unique personality and story to tell.

Whether you’re drawn to the buzzing energy of downtown or the serenity of the waterfront, you’ll find plenty of neighborhoods to explore in Charleston that reflect the city’s rich past and vibrant present.

French Quarter

Just a five-minute stroll from The Nickel Hotel, the French Quarter is Charleston’s oldest neighborhood and arguably its most atmospheric. Bordered by Broad Street, East Bay, and the Cooper River, this area is packed with art galleries, historic churches, cobblestone alleyways, and landmarks like the Dock Street Theatre and the Old Slave Mart Museum.

The French Quarter is also home to some of the city’s finest colonial architecture, including pastel-painted buildings and wrought-iron balconies reminiscent of its European namesake. On First Fridays, the area’s many art galleries open their doors for evening receptions, offering a perfect chance to mingle with locals and view contemporary Southern art.

South of Broad

An easy 12-minute walk from the hotel, South of Broad is one of Charleston’s most iconic and affluent neighborhoods. This area includes the famous Battery promenade and Rainbow Row, a colorful series of 18th-century townhouses that have become a symbol of Charleston.

Tree-lined streets, elegant mansions, and ocean breezes make for an inviting atmosphere. Walking through South of Broad feels like stepping into a history book, with its iron gates, hidden gardens, and views of Charleston Harbor. It’s a quiet neighborhood perfect for morning walks, historic sightseeing, and just soaking in the city’s charm.

Harleston Village

About a 15-minute walk or quick pedicab ride from The Nickel Hotel, Harleston Village is a leafy, residential area anchored by the College of Charleston. Its youthful energy blends seamlessly with centuries-old homes and shady live oaks.

Spend some time exploring Marion Square or grabbing coffee along Wentworth or George Street. The college campus is a highlight here, known for its beautiful brick paths and Greek Revival buildings. Harleston Village strikes a perfect balance between Charleston’s historic roots and modern vibrancy.

Sugar Bakeshop Charleston SC

Cannonborough/Elliotborough

The Nickel Hotel is located in the trendy Cannonborough/Elliotborough neighborhood. Once a quiet residential area, this district has blossomed into a creative hub filled with indie boutiques, coffee shops, bakeries, and small restaurants.

You’ll find spots like Sugar Bakeshop and Xiao Bao Biscuit, which offer innovative cuisine in stylish settings. This is a favorite neighborhood among young locals, and its easy-going atmosphere makes it one of the most welcoming and walkable in the city.

Upper King Street

The Nickel Hotel is located on Upper King Street, which is often referred to as Charleston’s “uptown“ nightlife and dining district. What was once a quiet extension of downtown has evolved into one of the city’s liveliest stretches.

Here you’ll find trendy cocktail bars, award-winning restaurants, and late-night hangouts that attract both locals and visitors. Notable spots include The Ordinary, The Darling Oyster Bar, and Prohibition. It’s a great neighborhood for dinner, drinks, and people-watching after a day of sightseeing.

Ansonborough

Only a 10-minute walk from the hotel, Ansonborough is one of Charleston’s first planned neighborhoods, dating back to the 18th century. It’s a beautiful blend of restored historic homes and quiet side streets, sitting just inland from the Charleston City Market.

This is a great neighborhood for architectural walking tours or relaxing with a cup of coffee in a nearby courtyard. Its proximity to both King Street and the waterfront makes it a hidden gem that feels both residential and centrally located.

Eastside

A 6-minute drive from The Nickel Hotel, or a longer walk, will bring you to Eastside, a fast-evolving neighborhood with strong African American heritage and roots in Charleston’s Gullah culture. It’s home to the Philip Simmons House, honoring the legendary ironwork artisan, and the International African American Museum, an important new addition to Charleston’s cultural landscape.

Eastside is also adjacent to Hampstead Mall Park and boasts a growing selection of creative spaces and local eateries. As Charleston continues to evolve, Eastside straddles both the city’s past and its future.

Tree with pink flowers with a house in the background Charleston SC

Westside & Wagener Terrace

A short 10-minute drive from downtown and The Nickel Hotel, Westside and Wagener Terrace are popular with young professionals and families. These neighborhoods offer a quieter, more residential feel with easy access to Hampton Park, one of the city’s most beautiful green spaces.

Rodney Scott’s BBQ is a neighborhood favorite restaurant, and there’s a growing buzz around the area's food and coffee scene. If you’re looking to explore a more local side of Charleston away from the tourist crowds, this is the place for you.

Avondale

Located across the Ashley River, Avondale is about a 12-minute drive from The Nickel Hotel and well worth the trip. Known for its artsy vibe, vintage stores, and mural-covered buildings, this West Ashley neighborhood has a fun, funky energy.

It’s also home to a host of beloved eateries like Highfalutin Coffee Roasters and Triangle Char & Bar. It’s the kind of place where you’ll find craft beer lovers, creative professionals, and families all hanging out at sidewalk cafes or the Saturday farmers market.

North Central & NoMo

Just a 7-minute drive north of The Nickel Hotel, North Central and NoMo (North Morrison) have transformed into hotspots for innovation and small business. The Charleston Tech Center, breweries like Revelry, and standout eateries like Home Team BBQ on Williman Street have helped turn this former industrial zone into one of Charleston’s newest and most dynamic neighborhoods.

The area blends edgy energy with the city’s traditional aesthetic—think converted warehouses, shipping-container pop-ups, and rooftop views. If you’re seeking creative inspiration, this is the place to find it.

Staying at the Center of It All

With so many neighborhoods to explore in Charleston, it’s clear the city’s beauty lies in its variety. From the colonial elegance of South of Broad to the up-and-coming vibrancy of NoMo and Eastside, each area brings something different to your visit.

The Nickel Hotel is perfectly situated in Charleston’s Historic District, making it an ideal home base for discovering the city’s neighborhoods on foot, by bike, or by car. 

If you're looking for a stylish and central location from which to explore all that Charleston has to offer, book a stay at The Nickel Hotel for the perfect choice.